BOTANICA FARMACEUTICA APPLICATA

Academic Year 2024/2025 - Teacher: ROSARIA ACQUAVIVA

Expected Learning Outcomes

Knowledge and understanding: the course provides the tools for the recognition of the main plants of pharmaceutical and herbal interest

Ability to apply knowledge and understanding: the student acquires the skills necessary to understand the use and use of medicinal plants in the pharmaceutical and herbalist industry

Learning skills: the student becomes able to recognize and identify plants of specific pharmaceutical and herbal interest

Making judgments: the student develops his critical ability in knowing how to recognize a medicinal plant.

Ability to solve a problem: the student is encouraged to recognize the botanical and pharmaceutical characteristics of medicinal plants

Course Structure

The course will be structured in frontal teaching with power point projection and/or short films. During the course there will be exercises and problem based learning. Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Information for students with disabilities and / or SLD: To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the teaching objectives and specifications needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of the Department, prof.ssa Santina Chiechio.

Required Prerequisites

Pharmaceutical Biology

Attendance of Lessons

Attendance is compulsory according to the regulations of the teaching regulations of the CdS in SFA as reported in the link: http://www.dsf.unict.it/corsi/l-29_sfa/regolamento-didattico

Detailed Course Content

The Applied Pharmaceutical Botany course will be divided into face-to-face lectures (7 CFU) and shared and co-operative group laboratory exercises dedicated to recognising and identifying plants of specific herbal and pharmaceutical interest (1 CFU), during which students will be invited to participate in feedback assessment activities.
Introduction to the study of the Pharmaceutical Botany. Classification. species concept. taxonomic system and evolution of systems. Supply of Medicinal Plants.
Vegetative reproduction. Sexual reproduction. The biological cycles. 
Mushrooms. Morphology. The mycelium. Heterotrophy. Propagation. sexual reproduction. Systematics of mushrooms. Morphology, pharmaceutical and application interest of: Zygomycota, Ascomycota, Basidiomycota. Intoxication with mushrooms
Algae. General characters. Morphology, pharmaceutical and application interest of: Rhodophyta: Gelidiaceae: Gelidium Sp.; Gigartinaceae: Chondrus crispus; Phaeophyta: Laminariaceae: Laminaria sp., Fucus
Overview of lichens and mosses. Morphology. utilization 
Spermatophytes. Gymnosperms. Morphology, ontogenetic cycle and practical interest of: Cycadophyta, Ginkgophyta, Coniferophyta, Ephedrales
Plant tissues: Meristematic and embryonic tissues. Parenchymal tissue, tegumental tissue, conducting tissue, segregating tissue, and mechanical tissue.
Angiosperms. The flower and its entirety. The inflorescences. Sexual reproduction. The seed. The fruit. Leaves.
Classification of angiosperms.
Primary and secondary metabolites

LILIOPSIDA (MONOCOTILEDONES)

ALLIACEAE: Allium sativum;

AGAVACEAE: Agave americana

ASPARAGACEAE: Convallaria majalis; Asparagus officinalis

LILIACEAE: Drimia maritima (Urginea maritima), Colchicum autumnale

ZINGIBERACEAE: Curcuma longa, Zingiber officinalis

 

MAGNOLIOPSIDA (DICOTILEDONES)

LAURACEAE: Cinnamomum sp., Laurus nobilis

PAPAVERACEAE: Papaver somniferum, Chelidonium majus

LAMIACEAE: Mentha sp., Lavandula officinalis, Thymus vulgaris, Salvia officinalis, Origanum sp., Melissa officinalis, Rosmarinus officinalis

BURSERACEAE: Boswellia

CACTACEAE: Opuntia ficus indica

CANNABACEAE: Cannabis sativa, Humulus lupulus

POLYGONACEAE: Reum sp.

STERCULIACEAE: Cola acuminata, C. vera, Teobroma cacao

FABACEAE: Glycyrrhiza glabra, Cassia senna

APIACEAE: Angelica archangelica, Foeniculum vulgare, Pimpinella anisum

EUPHORBIACEAE: Ricinus communis

ERICACEAE: Arctostaphylos uva-ursi; Vaccinum sp

RHAMNACEAE: Rhamnus frangula, R. purshiana

ERYTHROXYLACEAE: Erythroxylon coca

GROSSULARIACEAE: Ribes nigrum

MYRTACEAE: Melaleuca alternifolia

RUTACEAE: Citrus sp.

APOCYNACEAE: Strophanthus sp., Rauwolfia serpentine, Vinca

SOLANACEAE: Atropa belladonna, Datura stramonium, Nicotina tabacum

SCROPHULARIACEAE: Digitalis sp.

PASSIFLORACEAE: Passiflora incarnata

VALERIANACEAE: Valeriana officinalis

RUBIACEAE: Cinchona sp.,

ASTERACEAE: Matricaria chamomilla, Anthemis nobilis, Calendula officinalis, Cynara scolymus, Silybum marianum, Taraxacum officinale, Echinacea sp,.

VITACEAE: Vitis vinifera

The programme is divided into five parts according to a timeline of the topics covered.

Part 1: 1.5 CFU - 10.5h             

  • Introduction to the study of the Pharmaceutical Botany. Classification. species concept. taxonomic system and evolution of systems. Supply of Medicinal Plants.
  • Vegetative reproduction. Sexual reproduction. The biological cycles. 
  • Mushrooms. Morphology. The mycelium. Heterotrophy. Propagation. sexual reproduction. Systematics of mushrooms. Morphology, pharmaceutical and application interest of: Zygomycota, Ascomycota, Basidiomycota. Intoxication with mushrooms

Part 2: 1 CFU - 7h             

  • Algae. General characters. Morphology, pharmaceutical and application interest of: Rhodophyta: Gelidiaceae: Gelidium Sp.; Gigartinaceae: Chondrus crispus; Phaeophyta: Laminariaceae: Laminaria sp., Fucus
  • Overview of lichens and mosses. Morphology. utilization 

Part 3: 1 CFU - 7 h 

  • Spermatophytes. Gymnosperms. Morphology, ontogenetic cycle and practical interest of: Cycadophyta, Ginkgophyta, Coniferophyta, Ephedrales
  • Plant tissues: Meristematic and embryonic tissues. Parenchymal tissue, tegumental tissue, conducting tissue, segregating tissue, and mechanical tissue
  • Angiosperms. The flower and its elements. The inflorescences. Sexual reproduction. The seed. The fruit. Leaves.

Part 4: 3.5 CFU - 24.5h 

  • Classification of angiosperms.
  • Primary and secondary metabolites

LILIOPSIDA (MONOCOTILEDONES)

ALLIACEAE: Allium sativum;

AGAVACEAE: Agave americana

ASPARAGACEAE: Convallaria majalis; Asparagus officinalis

LILIACEAE: Drimia maritima (Urginea maritima), Colchicum autumnale

ZINGIBERACEAE: Curcuma longa, Zingiber officinalis

 

MAGNOLIOPSIDA (DICOTILEDONES)

LAURACEAE: Cinnamomum sp., Laurus nobilis

PAPAVERACEAE: Papaver somniferum, Chelidonium majus

LAMIACEAE: Mentha sp., Lavandula officinalis, Thymus vulgaris, Salvia officinalis, Origanum sp., Melissa officinalis, Rosmarinus officinalis

BURSERACEAE: Boswellia

CACTACEAE: Opuntia ficus indica

CANNABACEAE: Cannabis sativa, Humulus lupulus

POLYGONACEAE: Reum sp.

STERCULIACEAE: Cola acuminata, C. vera, Teobroma cacao

FABACEAE: Glycyrrhiza glabra, Cassia senna

APIACEAE: Angelica archangelica, Foeniculum vulgare, Pimpinella anisum

EUPHORBIACEAE: Ricinus communis

ERICACEAE: Arctostaphylos uva-ursi; Vaccinum sp

RHAMNACEAE: Rhamnus frangula, R. purshiana

ERYTHROXYLACEAE: Erythroxylon coca

GROSSULARIACEAE: Ribes nigrum

MYRTACEAE: Melaleuca alternifolia

RUTACEAE: Citrus sp.

APOCYNACEAE: Strophanthus sp., Rauwolfia serpentine, Vinca

SOLANACEAE: Atropa belladonna, Datura stramonium, Nicotina tabacum

SCROPHULARIACEAE: Digitalis sp.

PASSIFLORACEAE: Passiflora incarnata

VALERIANACEAE: Valeriana officinalis

RUBIACEAE: Cinchona sp.,

ASTERACEAE: Matricaria chamomilla, Anthemis nobilis, Calendula officinalis, Cynara scolymus, Silybum marianum, Taraxacum officinale, Echinacea sp,.

VITACEAE: Vitis vinifera


Part 5: 1 CFU (Laboratory Activities) - 12h 

Tissue and plant recognition; classification and collection of Gymnosperms and Angiosperms. Theoretical-practical verification to be offered at the end of each group exercise.

Textbook Information

1.   Maugini E., Maleci Bini L., Mariotti Lippi M. - Manuale di Botanica Farmaceutica IX Ed. – PICCIN 2014

2.   Leporatti M., Foddai S., Tommasini L. - Testo atlante di anatomia vegetale e delle piante officinali – PICCIN 1997

3.   Poli F. - Biologia Farmaceutica - II Ed. - Pearson 2019

Course Planning

 SubjectsText References
1Concetto di specie. Sistema tassonomico ed evoluzione dei sistemi. Testi: 1: Capitolo 9-10; Testo 3: Capitolo 1-6-7-10
2La riproduzione vegetativa e sessuale. I cicli biologici. Testo 1: Capitolo 8;
3Funghi. Morfologia. Il micelio. Eterotrofia. Propagazione. Riproduzione sessuale. Sistematica dei Funghi. Morfologia, ciclo ontogenetico ed interesse applicativo di: Zygomycota, Ascomycota, Basidiomycota. Intossicazioni da funghiTesti: 1: Capitolo 11;
4Alghe. Caratteri generali. Morfologia, ciclo ontogenetico ed interesse applicativo di: Rhodophyta: Gelidiaceae: Gelidium Sp.; Gigartinaceae: Chondrus crispus; Phaeophyta: Laminariaceae: Laminaria sp., Fucus. Licheni. La simbiosi lichenica. Testi: 1: Capitolo 12-13;
5Morfologia. Utilizzazione Muschi. Le cormofite. Briofite. Hepatophyta. Bryophyta. Pteridofite. Testi: 1: Capitolo 14-15;
6Tessuti vegetali: Tessuti meristematici o embrionali. Tessuti adulti o definitivi: sistema parenchimatico, sistema tegumentale, sistema conduttore, sistema segregatore e sistema meccanico.
7Spermatofite. Gimnosperme. Morfologia, ciclo ontogenetico ed interesse applicativo di: Cycadophyta, Ginkgophyta, Coniferophyta, EphedralesTesti: 1: Capitolo 16;
8Angiosperme. Il fiore e i suoi elementi. Le infiorescenze. La riproduzione sessuale. Il seme. Il frutto. Le foglie.Classificazione delle Angiosperme. Metaboliti primari e secondari Testi: 1: Capitolo 2, 17;
9Applicazioni fito-farmaceutiche delle seguentii piante officinali:Capitolo 17; Testo 2
10LILIOPSIDA (MONOCOTILEDONES) ALLIACEAE: Allium sativum; AGAVACEAE: Agave americana ASPARAGACEAE: Convallaria majalis; Asparagus officinalis LILIACEAE: Drimia maritima (Urginea maritima), Colchicum autumnaleTesti: 1: Capitolo 17; Testo 2
11MAGNOLIOPSIDA (DICOTILEDONES) LAURACEAE: Cinnamomum sp., Laurus nobilis PAPAVERACEAE: Papaver somniferum, Chelidonium majus CANNABACEAE: Cannabis sativa. Humulus lupulus POLYGONACEAE: Reum sp. STERCULIACEAE: Cola acuminata, C. vera, Teobroma cacaoTesti: 1: Capitolo 17; Testo 2
12FABACEAE: Glycyrrhiza glabra EUPHORBIACEAE: Ricinus communis RHAMNACEAE: Rhamnus frangula, R. purshiana ERYTHROXYLACEAE: Erythroxylon coca APOCYNACEAE: Strophanthus sp.,Rauwolfia serpentina SOLANACEAE: Atropa belladonna, Datura stramonium, N. tabacumTesti: 1: Capitolo 17; Testo 2
13SCROPHULARIACEAE: Digitalis sp. VALERIANACEAE: Valeriana officinalis RUBIACEAE: Cinchona sp., ASTERACEAE: Matricaria chamomilla, Anthemis nobilis.Testi: 1: Capitolo 17; Testo 2

Learning Assessment

Learning Assessment Procedures

EVALUATIVE CRITERIA.
The final exam will be evaluated based on the following indicators weighted equally and consistent with what is described in the expected learning outcomes (Dublin Descriptors):
- personal processing skills and operational initiative;
- ability to consult and use bibliographic materials;
- expository skills;
- scientific understanding of the topic.
Therefore, the final grade takes into account various factors listed below.
Quality of knowledge, skills, competencies possessed and/or manifested:
(a) appropriateness, correctness and congruence of knowledge
(b) appropriateness, correctness and congruence of skills
(c) appropriateness, correctness and congruence of skills
Expository mode:
(a) Expressive ability;
(b) Appropriate use of discipline-specific language;
(c) Logical skills and consequentiality in linking content;
(d) Ability to connect different topics by finding common points and establishing a coherent overall pattern, i.e., taking care of structure, organization and logical connections of expository discourse;
(e) Ability to synthesize including through the use of the subject's own symbolism and the graphic expression of notions and concepts, in the form of, for example, formulas, diagrams, equations.
Relational qualities:
Willingness to exchange and interact with the lecturer during the interview.
Personal qualities:
(a) critical spirit;
(b) ability to self-evaluate;
(c) problem-solving skills;
(d) ability to make decisions.
 
Based on the above, the rating can be:
(a) Sufficient (18 to 20/30)
Candidate demonstrates little acquired knowledge, superficial level, many gaps. Modest expressive skills, but still sufficient to sustain a coherent dialogue; logical skills and consequentiality in connecting topics of elementary level; poor synthesis skills and rather stunted graphic expression skills; poor interaction with the lecturer during the interview.
(b) Fair (21 to 23)
Candidate demonstrates fair acquisition of notions, but little in-depth study, few gaps; more than sufficient expressive skills to sustain a coherent dialogue; acceptable command of scientific language; logical skills and consequentiality in connecting topics of moderate complexity; more than sufficient ability to synthesize and acceptable graphic expression skills.
Example Questions: 1.Describe the morphology and classification of the plant body 2. Describe the morphology of meristematic tissues 4. Characteristics and function of primary and secondary metabolites 5. Biotechnology of medicinal plants. 6. Medicinal plants for the production of hormones, vaccines, and natural and bioactive products.
(c) Good (24 to 26)
The candidate demonstrates a fairly broad background, moderate depth of knowledge, with small gaps; satisfactory expressive skills and significant mastery of scientific language; well-detectable dialogical skills and critical spirit; good synthesis skills and more than acceptable graphical expression skills.
(d) Excellent (27 to 29)
The candidate demonstrates a very extensive, well-developed body of knowledge, with marginal gaps; remarkable expressive skills and high mastery of scientific language; remarkable dialogical ability, good competence and relevant aptitude for logical synthesis; high synthesis and graphic expression skills.
(e) Excellent (30)
The candidate demonstrates a very extensive and in-depth knowledge base, any gaps irrelevant; high expressive ability and high mastery of scientific language; remarkable dialogical ability, marked aptitude for making connections between different topics; excellent synthesis ability and great familiarity with graphic expression.
Honors are awarded to candidates who are clearly above average, and whose possible limitations in notional, expressive, conceptual, and logical skills are on the whole completely irrelevant.

The exam dates are published on the site of the Department of Drug Sciences http://www.dsf.unict.it/sites/default/files/files/ESAMI%20CDL%20SFA(13).pdf Learning assessment may also be carried out on line, should the conditions require it. Information for students with disabilities and / or SLD: To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the teaching objectives and specifications needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of the Department, prof.ssa Santina Chiechio

 Example Questions 1. Descrivere la morfologia e la classisicazione di un lichene 2. Descrivere morfologia di un'alga rhodophyta ed il ciclo biologico delle Florideophycidae 3. Descrivere la morfologia e le caratteristiche riproduttive delle briofite 4. Descrivere le caratteristiche botaniche e farmaceutiche di Digitalis purpurea 5. Descrivere le caratteristiche botaniche e farmaceutiche di Allium sativum

Examples of frequently asked questions and / or exercises

1. Describe the morphology and classification of a lichen 

2. Describe morphology of a rhodophyta alga and the life cycle of the Florideophycidae 

3. Describe the morphology and reproductive characteristics of bryophytes

4. Describe the botanical and pharmaceutical characteristics of Digitalis purpurea

5. Describe the botanical and pharmaceutical characteristics of Allium sativum