Prodotti della ricerca / Research products

Prodotti della ricerca (ultimo aggiornamento 12/12/2024):

 

Pubblicazioni scientifiche pubblicate nell’anno 2024 e riportanti come afferenza di uno o più autori il Centro NANOMED:

1. G. Greco, A. Agafonova, A. Cosentino, N. Cardullo, V. Muccilli, C. Puglia, C.D. Anfuso, M.G. Sarpietro, G. Lupo. Solid Lipid Nanoparticles Encapsulating a Benzoxanthene    Derivative in a Model of the Human Blood–Brain Barrier:    Modulation of Angiogenic Parameters and Inflammation in Vascular Endothelial Growth Factor-Stimulated Angiogenesis.  Molecules 2024, 29, 3103. https://doi.org/10.3390/molecules29133103.
2. Greco, G.; Sarpietro, M.G. Liposome-Assisted Drug Delivery in the Treatment of Multiple Sclerosis. Molecules 2024, 29, 4689. review https:// doi.org/10.3390/molecules29194689.
3. Dell'Albani P, Carbone C, Sposito G, Spatuzza M, Chiacchio MA, Grasso R, Legnani L, Santonocito D, Puglia C, Parenti R, Puglisi G, Campisi A. Effect of Ferulic Acid Loaded in Nanoparticle on Tissue Transglutaminase Expression Levels in Human Glioblastoma Cell Line. Int J Mol Sci. 2024 Aug 1;25(15):8397. doi: 10.3390/ijms25158397.
4. Pignatello R, Almeida H, Santonocito D, Puglia C. New Challenges in Ocular Drug Delivery. Pharmaceutics. 2024 Jun 11;16(6):794. doi: 10.3390/pharmaceutics16060794.
5. Santonocito D, Puglia C, Montenegro L. Effects of Lipid Phase Content on the Technological and Sensory Properties of O/W Emulsions Containing Bemotrizinol-Loaded Nanostructured Lipid Carriers. Cosmetics 2024, 11, 123. https://doi.org/10.3390/cosmetics11040123.
6. Finocchiaro M., Russo N., Fazio N.A., Gajewska J., Scalia G., Chajęcka-Wierzchowska W., Pino A., Caggia C., Randazzo CL. 2024. Unveiling the culturable ocular microbiota: phenotypic characterization, molecular typing and study of clonal relatedness within the staphylococci group. HELIYON-D-24-22157R2.
7. Nabil Chems Eddine, Maria Alessandra Ragusa, Dušan D. Repovš. On the concentration-compactness principle for anisotropic variable exponent Sobolev spaces and its applications. Fractional Calculus and Applied Analysis (2024) 27:725–756 https://doi.org/10.1007/s13540-024-00246-8.
8. Cinzia Cimino, Angela Bonaccorso, Barbara Tomasello, Giovanni Anfuso Alberghina, Teresa Musumeci, Carmelo Puglia, Rosario Pignatello, Agostino Marrazzo, Claudia Carbone. W/O/W Microemulsions for Nasal Delivery of Hydrophilic Compounds: A Preliminary Study. Journal of Pharmaceutical Sciences, Volume 113, Issue 6, 2024, Pages 1636-1644, ISSN 0022-3549, https://doi.org/10.1016/j.xphs.2024.01.013.
9. Cinzia Cimino, Elena Sánchez López, Angela Bonaccorso, Lorena Bonilla, Teresa Musumeci, Josefa Badia, Laura Baldomà, Rosario Pignatello, Agostino Marrazzo, Carla Barbaraci, María Luisa García, Claudia Carbone. In vitro and in vivo studies of ocular topically administered NLC for the treatment of uveal melanoma. International Journal of Pharmaceutics, Volume 660, 2024, 124300, ISSN 0378-5173, https://doi.org/10.1016/j.ijpharm.2024.124300.
10. Lorena Bonilla-Vidal, Marta Espina, María Luisa García, Cinzia Cimino, Claudia Carbone, Laura Baldomà, Josefa Badia, Anna Gliszczynska, Eliana B. Souto, Elena Sánchez-López. Melatonin loaded nanostructured lipid carriers for the treatment of uveal melanoma. Journal of Drug Delivery Science and Technology, Volume 100, 2024, 106057, ISSN 1773-2247, https://doi.org/10.1016/j.jddst.2024.106057.
11. Cinzia Cimino, Elide Zingale, Angela Bonaccorso, Teresa Musumeci, Claudia Carbone, Rosario Pignatello.From Preformulative Design to In Vivo Tests: A Complex Path of Requisites and Studies for Nanoparticle Ocular Application. Part 1: Design, Characterization, and Preliminary In Vitro Studies. Molecular Pharmaceutics 2024, 21, 12, 6034-6061, https://doi.org/10.1021/acs.molpharmaceut.4c00554.
12. Cinzia Cimino, Lorena Bonilla Vidal, Federica Conti, Elena Sánchez López, Claudio Bucolo, Maria Luisa García, Teresa Musumeci, Rosario Pignatello, Claudia Carbone. From Preformulative Design to in Vivo Tests: A Complex Path of Requisites and Studies for Nanoparticle Ocular Application. Part 2: In Vitro, Ex Vivo, and In Vivo Studies. Molecular Pharmaceutics 2024, 21, 12, 6062?6099, https://doi.org/10.1021/acs.molpharmaceut.4c00725.
13. Grazia M. L. Consoli, Ludovica Maugeri, Nicolò Musso, Antonino Gulino, Luisa D’Urso, Paolo Bonacci, Gianpiero Buscarino, Giuseppe Forte, and Salvatore Petralia. One-Pot Synthesis of Luminescent and Photothermal Carbon Boron-Nitride Quantum Dots Exhibiting Cell Damage Protective Effects. Adv. Healthcare Mater. 2024, 2303692. DOI: 10.1002/adhm.202303692.
14. Grazia M. L. Consoli, Ludovica Maugeri, Giuseppe Forte, Gianpiero Buscarino, Antonino Gulino, Luca Lanzano`, Paolo Bonacci, Nicolo` Musso and Salvatore Petralia. Red light-triggerable nanohybrids of graphene oxide, gold nanoparticles and thermo-responsive polymers for combined photothermia and drug release effects. Cite this: J. Mater. Chem. B, 2024, 12, 952. DOI: 10.1039/d3tb01863f.
15. Bonaccorso A, Ortis A, Musumeci T, Carbone C, Hussain M, Di Salvatore V, Battiato S, Pappalardo F, Pignatello R. Nose-to-Brain Drug Delivery and Physico-Chemical Properties of Nanosystems: Analysis and Correlation Studies of Data from Scientific Literature. Int J Nanomedicine. 2024 Jun 11;19:5619-5636. doi: 10.2147/IJN.S452316.
16. Zingale, E., Bonaccorso, A., D’Amico, A. G., Lombardo, R., D’Agata, V., Rautio, J., & Pignatello, R. (2024). Formulating Resveratrol and Melatonin Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Ocular Administration Using Design of Experiments. Pharmaceutics, 16(1), 125.
17. Zingale, E., Bonaccorso, A., Spadaro, A., Carbone, C., Musumeci, T., Sasmal, P. K., ... & Pignatello, R. (2024). Lipid-based nanocarriers mediated Axitinib retinal delivery after topical instillation: Formulations setting up and in vivo evidence. Journal of Drug Delivery Science and Technology, 100, 106026.
18. Cristaldi, Antonio; Oliveri Conti, Gea; Pellitteri, Rosalia; La Cognata, Valentina; Copat, Chiara; Pulvirenti, Eloise; Grasso, Alfina; Fiore, Maria; Cavallaro, Sebastiano; Dell'Albani, Paola; Ferrante, Margherita. In vitro exposure to PM2.5 of olfactory Ensheathing cells and SH-SY5Y cells and possible association with neurodegenerative processes. Environmental Research, 2024, 241, 117575.
19. Conti, Gea Oliveri; Giurdanella, Simona; Rapisarda, Paola; Leotta, Giulia; Cristaldi, Antonio; Favara, Claudia; Ferrante, Margherita. Toxicological Implications of Platinum Group Elements (PGEs): A Systematic Review of In Vivo and In Vitro Studies Using Mammalian Models. Frontiers in Bioscience - Landmark, 2024, 29(8), 304.

 

 

Articoli divulgativi pubblicati nell’anno 2024 e riportanti come afferenza di uno o più autori il Centro NANOMED:

1. C. Carbone, T. Musumeci, B. Tomasello, D. Manno, A. Bonaccorso, A. Serra, R. Pignatello. Oli Essenziali in Nanoparticelle Lipidiche: potenziale strategia coadiuvante nel trattamento delle malattie neurodegenerative per via intranasale. Innovazione in Botanicals, 4 (1) 2024, CEC editore, ISSN 2785-373X.

 

Partecipazione in occasione di congressi scientifici nazionali ed internazionali, nell’anno 2024 e riportanti come afferenza di uno o più autori il Centro NANOMED:

Poster:

1. D. Santonocito, C. Bucolo, G. Romeo, R. Pignatello and C. Puglia. NanoRET- Patologie Neurodegenerative Retiniche: Nuovi Approcci Farmacologici E Nanotecnologici.  Piaceri Day 2024. Università di Catania, 11 luglio 2024.
2. Cinzia Cimino, Teresa Musumeci, Claudia Carbone, Angela Bonaccorso, Agata G. Copani, Rosario Pignatello. Ataxia telangiectasia: drug repositioning for pediatric treatment of a rare genetic neurological disease. Formulating better medicines for children, 16th EuPFI Conference 2024, 17-19/09/2024, Rotterdam, Paesi Bassi.
3. Cinzia Cimino, Angela Bonaccorso, Teresa Musumeci, Rosario Pignatello, Claudia Carbone. Veicolazione di oli essenziali in carrier lipidici nanostrutturati per la potenziale somministrazione cutanea e intranasale. Farmacista: l’evoluzione della professione, XXXVI congresso internazionale Società Farmaceutica del Mediterraneo Latino 2024, 26-28/09/2024, Catania, Italia.
4. Zingale Elide, Masuzzo Sebastiano, Pignatello Rosario. Self-nanoemulsifying drug delivery systems: a new approach for the topical treatment of degenerative ocular diseases. Farmacista: l’evoluzione della professione, XXXVI congresso internazionale Società Farmaceutica del Mediterraneo Latino 2024, 26-28/09/2024, Catania, Italia.
5. Salamone S., Manin S., Musumeci T., Pignatello R. "Nose-to-brain delivery of nanomedicine to delay cognitive impairment related to metabolic syndrome", Forum Nazionale sulla medicina di precisione, June from 14th to 16th, 2024, University of Palermo.
6. Manin S., Musumeci T., Carbone C., Bonaccorso A., Pignatello R. "Isoliquiritigenin nanocrystals: a cutting-edge nanomedicine approach for neurodegenerative and metabolic diseases therapy ", 1st SITELF National PhD summer school (XXIII ADRITELF National PhD school) September from 2th to 4th, 2024, University of Pavia.
7. Manin S., Salamone S., Musumeci T., Carbone C., Bonaccorso A., Pignatello R. “Isoliquiritigenin nanocrystals as a promising strategy for the treatment of metabolic diseases and cognitive impairment”, XXXVI congresso internazionale Società Farmaceutica del Mediterraneo Latino 2024, 26-28/09/2024, Catania, Italia.
8. Salamone S., Craparo F., Bonaccorso A., Carbone C., Pellitteri R., Scialabba C., Musumeci T., Cavallaro G., Pignatello R. NiR labelled PEG-PLGA/ PHEA-g-Dy700-g-PLA nanoparticles as a powerful tool for optical imaging.  1st SITELF National PhD summer school (XXIII ADRITELF National PhD school). Sept. 2-4, 2024, Pavia, Italy.

 

Comunicazioni orali:

1. Diroximel fumarate loaded Solid Lipid Nanoparticles (DRF-SLN) as Potential Carriers for the Treatment of Multiple Sclerosis: Formulation Development and Optimization. Debora Santonocito, Katia Mangano, Maria Grazia Sarpietro, Giuliana Greco, Agatina Campisi, Giuseppe Romeo and Carmelo Puglia.  AMYC BIOMED 2024 Autumn Meeting for Young Chemists in Biomedical Sciences 5th Edition. Sapienza University of Rome, 23*d-25th September 2024, Roma.
2. Ocular Drug Delivery: Present Innovations and Future Challenges. Debora Santonocito, Rosario Pignatello, Maria Grazia Sarpietro, Giuliana Greco and Carmelo Puglia. XXXVI Congresso internazionale della Società Farmaceutica del Mediterraneo. Catania 26-28 settembre 2024, Sala Conferenze Federfarma Catania.
3. Development of Self-Nanoemulsifying Drug Delivery Systems for Sirt-1 agonist compounds in ocular degenerative diseases. Elide Zingale and Rosario Pignatello. Nanomib 2024 conference “Recent advances in nanomedicine: opportunities and challenges” 29 Febbraio-1 Marzo 2024 (Università degli studi di Milano Bicocca).
4. Development of dual drug-loaded hydrogel scaffolds for ocular implantation combining microfluidics and coaxial 3D-printing techniques. Elide Zingale, Edward Weaver, Rosario Pignatello and Dimitrios A Lamprou. UKICRS Annual Symposium (7th June 2024, Cardiff, UK).
5. Engineering intravitreal implant combining microfluidics and 3D-printing techniques for synergistic delivery of Sirt1 agonists. Elide Zingale, Edward Weaver, Pietro Maria Bertelli, Imre Lengyel, Rosario Pignatello and Dimitrios A. Lamprou. Autumn Meeting of Young Chemists in Biomedical Sciences 2024 (AMYC-BIOMED 2024) Sapienza University of Rome, 23-25 Settembre 2024, Rome (Italy).
6. Step by step development of self-emulsifying drug delivery systems (snedds) for ocular delivery of sirt1 agonists. Elide Zingale and Rosario Pignatello. 1st SITELF National PhD summer school (XXIII ADRITELF National phd school) University of Pavia, 2 – 4 September 2024.